Biotin and derivatives
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | >98.7% | 456.41 | 100 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. It is for research use only and not sold to patients.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide-based cereblon ligand and NHS ester linker
- Targets cereblon
Medchemexpress LLC Biotin-H10 | 98.94% | 1822.22 | 10 MG
Biotin-H10 is a specific anterior gradient homolog 2 (AGR2) inhibitor, demonstrating a KD of 6.4 nM. It inhibits cancer cell viability and is intended for research use only.
- Inhibits cancer cells viability
- Specific AGR2 inhibitor with a KD of 6.4 nM
- Supplied as a white to off-white solid
- Store in sealed container, away from moisture and light
- Recommended storage for powder: -80°C for 2 years or -20°C for 1 year
- Recommended storage in solvent: -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO at 50 mg/mL (27.44 mM)
Medchemexpress LLC Biotin-PEG2-NH-Boc | 175885-18-4 | C21H38N4O6S | 1 G
Biotin-PEG2-NH-Boc is identified as a biotin-labeled, PEG-based linker used in the synthesis of PROTACs. These PROTACs are compounds designed with two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism exploits the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- Functions as a linker for targeted protein degradation research.
- Utilizes a biotin label.
- Peg-based structure.
- Acts through the ubiquitin-proteasome system.
- Facilitates selective protein degradation.
Medchemexpress LLC m-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 500 MG
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. These PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research purposes only.
- PEG-based PROTAC linker
- Enables the synthesis of PROTACs
- Utilizes the ubiquitin-proteasome system
- Achieves selective degradation of target proteins
- Suitable for research use only
Medchemexpress LLC Biotin-C5-azide | 1260586-88-6 | 98.9% | 255.34 g/mol | C10H17N5OS | 10 MG
Biotin-C5-Azide is a biotinylation reagent containing a terminal azide group for click chemistry. It is intended for research use to prepare biotinylated conjugates via copper-catalyzed or strain-promoted azide-alkyne cycloaddition.
Medchemexpress LLC Bis-biotin-PEG23 | 293298-36-9 | 97.8% | C68H128N6O27S2 | 10MG
Bis-Biotin-PEG23 is a polyethylene glycol (PEG)-based PROTAC linker bearing biotin groups at both termini, designed to facilitate the assembly of bifunctional molecules and to introduce biotin affinity tags for pull-down or detection assays. It is supplied as a solid with high specified purity and is intended for research applications requiring a hydrophilic, flexible spacer.
- Two terminal biotin groups for affinity capture and detection.
- Long PEG23 spacer provides flexibility and improved solubility.
- High purity suitable for analytical and synthetic workflows.
- Solid form allows convenient handling and storage.
- Storage under low temperature and inert atmosphere preserves stability.
eMolecules 2280998-74-3 | Medchem Express | m-PEG11-acid | 50mg | 721309591 | HY-140501 | MFCD27977512 | 544.635 | C24H48O13
Ambeed | 2-(4-Carbamimidoylphenyl)acetic acid hydrochloride | 100mg | 490510431 | A142490 | 52798-09-1 | MFCD11505975 | 214.650 | C9H11ClN2O2
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Medchemexpress LLC Sulfo-Cy3-NHS disodium | 865.90 g/mol | C36H41N3Na2O13S3 | 10 MG
Sulfo-Cy3-NHS disodium is a water-soluble Cyanine3 (Cy3) derivative bearing an NHS ester for amine-reactive conjugation. The sulfonate groups increase aqueous solubility, making this reagent suitable for labeling proteins, peptides, and antibodies for fluorescence detection and imaging.
- Water-soluble NHS ester for efficient labeling of primary amines.
- Improved aqueous solubility due to sulfonate groups.
- Suitable for conjugation to proteins, antibodies, and peptides.
- Enables fluorescence detection and imaging applications.
- Stable solid form for routine laboratory handling and storage per manufacturer instructions.
Medchemexpress LLC Azido-PEG16-NHS ester | 00-00-0 | 99.9% | C39H72N4O20 | 10MG
Azido-PEG16-NHS ester is a PEG-based bifunctional linker featuring an azide moiety and an N-hydroxysuccinimide (NHS) ester. It enables conjugation to primary amines via the NHS ester and subsequent click chemistry using the azide, making it suitable for bioconjugation, labeling, and PROTAC synthesis. The reagent is provided at high purity and is soluble in DMSO for convenient formulation.
Medchemexpress LLC (S,E)-TCO-NHS ester | 1610931-22-0 | MFCD24386372 | ≥98.0% | 267.28 g/mol | C13H17NO5 | 10 MG
TCO-NHS ester (axial) is a trans-cyclooctene N-hydroxysuccinimide ester used as an amine-reactive building block for bioorthogonal conjugation. It enables rapid inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazine partners and is suitable for labeling or modifying amine-containing small molecules and biomolecules in organic media. The reagent is supplied as a purified solid with supporting analytical documentation for research use.
- Amine-reactive NHS ester for efficient conjugation.
- Fast bioorthogonal iEDDA reactivity with tetrazines.
- Suitable for labeling and bioconjugation of biomolecules.
- High purity for reproducible experimental results.
- Analytical documentation available (SDS, COA, H-NMR).
Medchemexpress LLC Biotin-sar-oh | 154024-76-7 | 315.39 | C13H21N3O4S | 1 G
Biotin-sar-oh is a cleavable antibody-drug conjugate (ADC) linker bearing a biotin functionality, used in the synthesis of antibody-drug conjugates and probe development.
- Cleavable ADC linker for conjugation and release strategies.
- Biotinylated for affinity capture and detection.
- Molecular formula: C13H21N3O4S; molecular weight: 315.39.
- Available pack sizes: 250 mg and 1 g.
- CAS number: 154024-76-7.
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine conjugated to biotin | 133695-76-8 | MFCD01961045 | 97.5% | 974.36 | C51H96N3O10PS | 50 MG
DSPE-Biotin is a biotinylated phospholipid used as a lipid reagent for biochemical research, liposome formulation, and surface functionalization of nanoparticles. It enables biotin-mediated capture or labeling of lipid assemblies and supports drug-delivery and biochemical assay applications. Store cold and protect from light for best stability.
- Biotinylated phospholipid enabling strong biotin-avidin interactions.
- Suitable for liposome preparation and nanoparticle surface functionalization.
- Facilitates biotin-mediated capture and labeling of lipid assemblies.
- High purity (97.5%) for reproducible experimental results.
- Solid, off-white to light yellow appearance for easy handling.
- Storage: -20°C; in solvent: -80°C (6 months), -20°C (1 month); protect from light.
Medchemexpress LLC Endo-BCN-NHS carbonate | 1426827-79-3 | MFCD19705416 | 99.5% | 291.30 g·mol⁻¹ | C15H17NO5 | 50 MG
endo-BCN-NHS carbonate is an NHS-activated bicyclononyne carbonate reagent used for bioconjugation. It functionalizes primary amines to introduce BCN handles that enable strain-promoted azide-alkyne cycloaddition (SPAAC) for copper-free click chemistry, commonly applied to modify elastin-like proteins and to form cross-linked hydrogels for cell encapsulation studies.
- Reacts with primary amines to install BCN functional groups.
- Enables copper-free strain-promoted azide-alkyne cycloaddition (SPAAC).
- Facilitates hydrogel formation and protein cross-linking for cell encapsulation.
- High purity supports reproducible conjugation chemistry.
- Powder stable at -20°C for long-term storage; solvent stability varies.
Medchemexpress LLC Biotin-oxytocin (biotin-a-hypophamine; biotin-oxytocic hormone) | 99.3% | 1233.48 | C53H80N14O14S3 | 10 MG
Biotin-oxytocin is an N-terminally biotinylated form of the oxytocin peptide supplied for laboratory research use. The peptide retains the native disulfide-stabilized backbone while providing an N-terminal biotin tag for affinity capture, labeling, and detection in biochemical and cell-based assays. Supplied with supporting documentation including a datasheet and COA.
- 99.3% purity.
- Molecular weight 1233.48 Da.
- Sequence: biotin-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (disulfide Cys1-Cys6).
- Available sizes: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.
- Supplied with datasheet, COA, and SDS.
- Intended for research use only.
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 98.7% | 258.34 g/mol | C10H18N4O2S | 1 G
Biotin hydrazide is a carbonyl-reactive biotinylation reagent that forms hydrazone linkages with oxidized carbohydrates and other carbonyl groups. It is used to introduce a biotin tag for detection, affinity capture, and enrichment of labeled proteins and glycoconjugates in biochemical assays and proteomics workflows.
- Reacts selectively with aldehydes and ketones after oxidation.
- Enables streptavidin-based detection and affinity purification.
- Suitable for labeling glycoproteins following periodate oxidation.
- Supplied as a solid reagent for solution preparation and storage.
- High purity for reproducible analytical and preparative work.